Antibiogram and Genotypic Analysis using 16S rDNA after Biofield Treatment on Morganella morganii

نویسندگان

  • Mahendra Kumar Trivedi
  • Alice Branton
  • Dahryn Trivedi
  • Gopal Nayak
  • Mayank Gangwar
  • Snehasis Jana
چکیده

Morganella species are the clinically characterized in the tribe Proteeae [1]. Morganella species infections are less frequent in healthy individuals. Morganella morganii (M. morganii) is Gram-negative and facultative anaerobic bacterium of the family Enterobacteriaceae. It exists as commensal within the intestinal tract of humans, mammals, and reptiles as a normal flora [2]. Originally, it was reported to be as common cause of summer diarrhoea but later on, clinical infections associated with urinary tract, skin and soft tissue and hepatobiliary tract were reported [3]. They are motile, non-lactose fermenting, and have the capacity for urease production and show the presence of phenylalanine deaminase. Morganella associated infections are the fifth leading cause of UTIs in nursing home patients [4]. According to Warren et al. catheter-associated bacteriuria due to Morganella in long term care facilities has been reported [5]. Most of the infectious cases in microbiology laboratory were associated with urine, wounds, and from a variety of body fluids or tube drainage [6]. M. morganii bacteremia entry has involved hepatobiliary tract, as 64% cases are related to intraabdominal infections [7]. Morganella species show resistance against β-lactam antibiotics, usually due to the presence of chromosomally encoded β-lactamases belonging to the AmpC β-lactamase family. Most of the β-lactamase enzymes are inducible in nature only on exposure to antibiotics [8]. Continuous use of antibiotics leads to the high-level expression of a resistant isolate of M. morganii against second or third generation’s antibiotics [9]. Therefore, an alternative strategy is needed to alter the antimicrobial sensitivity profile against Morganella strain. Multidrug therapy and some alternate approach are required to treat the associated infections. Due to the several side effects alternate and complementary therapy approach are the best treatment strategies. Among various complementary and alternate treatment approach, biofield treatment may be one of the approach to alter the antimicrobial sensitivity.

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تاریخ انتشار 2015